Biochemie verzweigter Carbonsäuren. II. Mitteilung: Bakteriostatische und fungistatische Wirkung aliphatischer Carbonsäuren und Alkohole

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Abstract
Mycobacterium tuberculosis, Staphylococcus aureus, Trvchophvton gypseum, Torulopsis minor and M. smegmatis were examined in their response to homologous series of n-acids and their methyl derivatives, and n- and branched alcohols.The greatest growth inhibitions were observed with M. tuberculosis and smaller effects with T. gypseum. The others were either uninhibited or affected only by high concns. With alcohols the effectiveness increased with increasing chain length to the highest (C16) member tested. With acids the effectiveness increased to a range of C8-C14 (varying with different strains) and decreased as chain length was increased to C20. The methyl-branched derivatives of alcohols and acids were as effective as the unbranched parent substances.