Abstract
Twenty-two eyes [human] affected with keratoconjunctivitis sicca were subjected to double trials using the double-blind randomized cross-over technique. Polyvinyl alcohol in a 5% concentration improved the condition but liquid paraffin aggravated it, as estimated subjectively, and by the measurement of the break up time of the corneal film, and, finally, by the scoring of rose bengal vital staining of exposed cornea and conjunctiva. Oil is apparently contraindicated in keratoconjunctivitis sicca, and rose bengal scoring (modified Bijsterveld method) is a valuable aid in control of the sicca syndrome.

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