Dibenzyline in Vascular Disease of the Hands

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Abstract
In hands with vasospastic disease the blood flow remained unaltered by treatment with Dibenzyline, whereas the resting blood flow showed a significant decrease in hands with structural arterial disease. In all cases the skin temperature increased. Dibenzyline was not able to prevent the digital ischemia during cold exposure as did peripheral sympathetic nerve blockade. Side effects were frequent and marked among patients with vasospastic disease of the hands. In vasospastic feet the skin temperature likewise increased considerably, but the blood flow was unchanged. The muscle blood flow through the calf did not change after administration of Dibenzyline.