Topical Treatment of Pressure Ulcers: A Randomized Comparative Trial of Varidase® and Zinc Oxide
- 1 January 1985
- journal article
- research article
- Published by Taylor & Francis in Scandinavian Journal of Plastic and Reconstructive Surgery
- Vol. 19 (1) , 97-100
- https://doi.org/10.3109/02844318509052871
Abstract
In a single-blind, randomized trial, the efficacy of topical streptokinase-streptodornase (Varidase®) solution was compared with that of zinc oxide on necrotic pressure ulcers in 28 patients. The effectiveness was determined by measuring the necrosis removal within 8 weeks. This occurred in 6 patients (43%) treated with Varidase® and in 7 (50%) treated with zinc oxide. The statistical tests applied showed no significant difference between the two treatments despite the use of a high power (1-β=0.95). The data suggest that the two regimens are about equally effective in the treatment of necrotic tissue.This publication has 17 references indexed in Scilit:
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