Distribution and tissue dose of intraperitoneally administered radioactive chromic phosphate (32P) in New Zealand white rabbits.
- 1 March 1980
- journal article
- research article
- Published by Radiological Society of North America (RSNA) in Radiology
- Vol. 134 (3) , 729-734
- https://doi.org/10.1148/radiology.134.3.7355227
Abstract
Radiophosphorus (32P) has become the preferred radioisotope for i.p. radiotherapy in the adjuvant treatment of ovarian cancer [in humans]. In a study of the distribution and tissue dose of i.p. administered 32P in rabbits, effective half-lives of 32P and the radiation dose absorbed by intra-abdominal tissues were determined. 32P is not uniformly distributed over the peritoneal surfaces and many areas are minimally irradiated. Apparently, a significant fraction of the 32P distribution is systemic and the .beta.-ray dose for intra-abdominal tissues is much lower than suggested by theoretical models.This publication has 4 references indexed in Scilit:
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- Uptake of Colloidal Chromic Radiophosphate (P32) by Bone and GonadsRadiology, 1965
- Adjuvant Use of Radioactive Colloids in the Treatment of Carcinoma of the OvaryRadiology, 1964
- DISTRIBUTION OF COLLOIDAL RADIOACTIVE CHROMIC PHOSPHATE AFTER INTRACAVITARY ADMINISTRATION IN THE RAT1953