The frequency of the fragile X chromosome among schoolchildren in Coventry.
Open Access
- 1 October 1986
- journal article
- research article
- Published by BMJ in Journal of Medical Genetics
- Vol. 23 (5) , 396-399
- https://doi.org/10.1136/jmg.23.5.396
Abstract
A population study has been carried out among schoolchildren in the City of Coventry in order to ascertain the frequency of mental retardation associated with the fragile X chromosome. The prevalence of the fragile X mental retardation syndrome in the 11 to 16 year age group (the age of greatest ascertainment) was about 1.0 per 1,000 and therefore indicates that the syndrome is a major cause of mental retardation.This publication has 9 references indexed in Scilit:
- Twelve families with fragile X(q27).Journal of Medical Genetics, 1986
- A community study of severe mental retardation in the West Midlands and the importance of the fragile X chromosome in its aetiology.Journal of Medical Genetics, 1985
- Heritable fragile sites on human chromosomes XII. Population CytogeneticsAnnals of Human Genetics, 1985
- The marker (X) syndrome: a cytogenetic and genetic analysisAnnals of Human Genetics, 1984
- Fragile X syndrome in mildly mentally retarded children in a Northern Swedish county. A prevalence studyClinical Genetics, 1983
- The diagnosis and frequency of X‐linked conditions in a cohort of moderately retarded males with affected brothersAmerican Journal of Medical Genetics, 1983
- Heterozygous Expression of X-Linked Mental Retardation and X-Chromosome Marker Fra(X)(Q27)New England Journal of Medicine, 1980
- Nonspecific X‐linked mental retardation II: The frequency in British ColumbiaAmerican Journal of Medical Genetics, 1980
- HERITABLE FRAGILE SITES ON HUMAN-CHROMOSOMES .1. FACTORS AFFECTING EXPRESSION IN LYMPHOCYTE CULTURE1979