Twelve families with fragile X(q27).
Open Access
- 1 October 1986
- journal article
- research article
- Published by BMJ in Journal of Medical Genetics
- Vol. 23 (5) , 400-406
- https://doi.org/10.1136/jmg.23.5.400
Abstract
Through a community study of boys requiring special education for the severely mentally retarded, 12 families were ascertained in which the fragile X was found to be segregating. By assiduous follow up of these families, it was found that in only four of them could male transmission be ruled out from the grandparents' or great grandparents' generation and that the segregation ratios are disturbed.This publication has 17 references indexed in Scilit:
- A community study of severe mental retardation in the West Midlands and the importance of the fragile X chromosome in its aetiology.Journal of Medical Genetics, 1985
- Further segregation analysis of the fragile X syndrome with special reference to transmitting malesHuman Genetics, 1985
- The marker (X) syndrome: a cytogenetic and genetic analysisAnnals of Human Genetics, 1984
- Fragile X trait in a large kindred: transmission also through normal males.Journal of Medical Genetics, 1983
- The fragile X chromosome in a large Indian kindredClinical Genetics, 1983
- Marker X syndrome in an oriental family with probable transmission by a normal maleAmerican Journal of Medical Genetics, 1982
- Fragile (X)(q27) sites in a pedigree with female carriers showing mild to severe mental retardation.Journal of Medical Genetics, 1982
- TRANSMISSION OF FRAGILE (X) (q27) SITE FROM A MALEThe Lancet, 1981
- 5-Fluoro-2'-deoxyuridine induction of the fragile site on Xq28 associated with X linked mental retardation.Journal of Medical Genetics, 1981
- Heterozygous Expression of X-Linked Mental Retardation and X-Chromosome Marker Fra(X)(Q27)New England Journal of Medicine, 1980