Hypokalemic periodic paralysis. Experimental precipitation with sodium liothyronine

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Abstract
The effect of sodium liothyronine was investigated in a 44-year-old Japanese man who had been freed of thyrotoxic periodic paralysis 7 years previously after subtotal thyrotectomy. Gradually increasing doses of liothyronine were administered until the patient began to have typical attacks of nocturnal periodic paralysis associated with hypokalemia. These attacks subsided soon after the withdrawal of the liothyronine. The patient with thyrotoxic periodic paralysis is cured from further attacks of periodic paralysis when the hyperthyroidism is cured, but the basic susceptibility to attacks of periodic paralysis apparently is still present.

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