Gangrenous Ulcer and Septicemia Due to Citrobacter

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Abstract
LEUKEMIC patients provide a setting in which organisms of low virulence may flourish and unusual infections become commonplace.1 2 3 4 5 6 This is the first report to incriminate citrobacter as a cause of a necrotizing skin infection with septicemia in such a setting.Case ReportA 55-year-old woman was found to have acute myelomonocytic leukemia in March, 1968. Partial remission was induced and maintained with hydroxyurea and prednisone. The latter was discontinued because of myopathy. Four months later she relapsed. Ten days of therapy with intravenous cytosine arabinoside and oral thioguanine resulted in bone-marrow aplasia and peripheral agranulocytosis. An extremely tender ecchymosis, 8 . . .

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