Ras-mediated Loss of the Pro-apoptotic Response Protein Par-4 Is Mediated by DNA Hypermethylation through Raf-independent and Raf-dependent Signaling Cascades in Epithelial Cells
Open Access
- 1 June 2005
- journal article
- Published by Elsevier
- Vol. 280 (24) , 23363-23370
- https://doi.org/10.1074/jbc.m503083200
Abstract
No abstract availableKeywords
This publication has 51 references indexed in Scilit:
- Targeting RAS signalling pathways in cancer therapyNature Reviews Cancer, 2003
- Distinct requirements for Ras oncogenesis in human versus mouse cellsGenes & Development, 2002
- Opposing Roles of the Extracellular Signal-Regulated Kinase and p38 Mitogen-Activated Protein Kinase Cascades in Ras-Mediated Downregulation of TropomyosinMolecular and Cellular Biology, 2002
- Oncogenic Ras Blocks Anoikis by Activation of a Novel Effector Pathway Independent of Phosphatidylinositol 3-KinaseMolecular and Cellular Biology, 2001
- The Hallmarks of CancerCell, 2000
- Negative regulation of Par-4 by oncogenic Ras is essential for cellular transformationOncogene, 1999
- Activation of mitogen-activated protein kinase is necessary but not sufficient for proliferation of human thyroid epithelial cells induced by mutant RasOncogene, 1999
- Ras, but not Src, transformation of RIE-1 epithelial cells is dependent on activation of the mitogen-activated protein kinase cascadeOncogene, 1998
- New 5′ Regions of the Murine and Human Genes for DNA (Cytosine-5)-methyltransferaseJournal of Biological Chemistry, 1996
- Altered Growth of Human Colon Cancer Cell Lines Disrupted at Activated Ki- rasScience, 1993