EFFECTS OF SALICYLATE ON GLUTAMATE DEHYDROGENASE AND GLUTAMATE DECARBOXYLASE
- 1 August 1963
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 88 (2) , 346-349
- https://doi.org/10.1042/bj0880346
Abstract
Salicylate inhibits glutamate-de-hydrogenase and glutamate-decarboxylase activities in vitro. The inhibition of glutamate dehydrogenase is reversible but does not involve competition with either glutamate or NAD; the inhibition of glutamate decarboxylase is irreversible. Preincubation of glutamate decarboxylase with pyridoxal phosphate reduces the degree of inhibition by salicylate.This publication has 10 references indexed in Scilit:
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