Simultaneous Determination of Methaqualone and Diazepam in Plasma by Derivative Spectroscopy
- 1 February 1992
- journal article
- pharmaceutical analysis
- Published by Taylor & Francis in Analytical Letters
- Vol. 25 (2) , 253-268
- https://doi.org/10.1080/00032719208018524
Abstract
A spectrophotometric method for the simultaneous determination of methaqualone and diazepam in plasma by second-derivative spectroscopy is reported. The proposed method is quite sensitive (it allows the determination of therapeutic levels of both pharmaceuticals) and easy to implement. It provided average recoveries of 93.75% and 99.04% for methaqualone and diazepam, respectively.Keywords
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