The assignment of the genes coding for human complement components C6 and C7 to chromosome 5
- 1 May 1990
- journal article
- Published by Wiley in Annals of Human Genetics
- Vol. 54 (2) , 141-147
- https://doi.org/10.1111/j.1469-1809.1990.tb00370.x
Abstract
A panel of 19 somatic cell hybrids was tested for the presence of human sequences coding for complement components C6 and C7 by restriction enzyme digestion and Southern blots probed with human C6 and C7 cDNA probes. C7 was also detected by amplifying part of the human gene in hybrid DNA using the polymerase chain reaction. Detection of human C6 and C7 was completely correlated with the presence of chromosome 5.Keywords
This publication has 18 references indexed in Scilit:
- Late-Acting Components of Complement: Their Molecular Biochemistry, Role in the Host Defense, and Involvement in PathologyPathology and Immunopathology Research, 1987
- Mapping of the gene coding for the human liver/bone/kidney isozyme of alkaline phosphatase to chromosome 1Annals of Human Genetics, 1986
- Assignment of the gene determining human carbonic anhydrase, CAI, to chromosome 8Annals of Human Genetics, 1986
- The Membrane Attack Complex of ComplementAnnual Review of Immunology, 1986
- C6 LINKAGE STUDIESInternational Journal of Immunogenetics, 1983
- Regulation of expression of liver‐specific enzymesAnnals of Human Genetics, 1982
- Regional assignments of the loci AK3, ACONs, and ASS on human chromosome 9Cytogenetic and Genome Research, 1979
- Assignment of the human acid α‐glucosidase gene (αGLU) to chromosome 17 using somatic cell hybridsAnnals of Human Genetics, 1979
- INHERITED STRUCTURAL VARIATION AND LINKAGE RELATIONSHIPS OF C7International Journal of Immunogenetics, 1978
- Chromosome assignment of some human enzyme loci: mitochondrial malate dehydrogenase to 7, mannosephosphate isomerase and pyruvate kinase to 15 and probably, esterase D to 13Annals of Human Genetics, 1975