Improved cortical histology after cementation with a new MMA‐DMA‐IBMA bone cement: An animal study

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Abstract
The histological response of bone to inert bone wax, conventional polymethylmethacrylate (PMMA), and a new formulation of bone cement, methylmethacrylate/n‐decylmethacrylate/isobornylmethacrylate (MMA/DMA/IBMA) was investigated in canine tibial diaphysis. The new formulation of cement is characterized by a reduced exothermic temperature at curing and reduced leakage of chemicals to the adjacent bone. In comparison with bone wax, the MMA/DMA/IBMA bone cement did not differ significantly with respect to periosteal apposition and bone remodeling, although a tendency to inhibit the biological response was encountered. The MMA/DMA/IBMA was clearly superior to PMMA bone cement in respect to both bone necrosis and repair, as well as bone remodeling. © 1993 John Wiley & Sons, Inc.