Nonlinear Pharmacokinetics
- 1 June 1991
- journal article
- research article
- Published by Springer Nature in Clinical Pharmacokinetics
- Vol. 20 (6) , 429-446
- https://doi.org/10.2165/00003088-199120060-00001
Abstract
Nonlinear pharmacokinetics (in other words, time or dose dependences in pharmacokinetic parameters) can arise from factors associated with absorption, first-pass metabolism, binding, excretion and...Keywords
This publication has 99 references indexed in Scilit:
- Clinical applicability of current pharmacokinetic models: Splanchnic elimination of 5-fluorouracil in cancer patientsJournal of Pharmacokinetics and Biopharmaceutics, 1988
- Interaction of disopyramide enantiomers for sites on plasma proteinLife Sciences, 1987
- In vivo interaction of the enantiomers of disopyramide in human subjectsJournal of Pharmacokinetics and Biopharmaceutics, 1986
- Phenytoin Michaelis-Menten Pharmacokinetics in Caucasian Paediatric PatientsClinical Pharmacokinetics, 1983
- Time course of carbamazepine self-inductionJournal of Pharmacokinetics and Biopharmaceutics, 1979
- Role of concentration-dependent plasma protein binding in disopyramide dispositionJournal of Pharmacokinetics and Biopharmaceutics, 1979
- Increased Plasma Protein Binding of Propranolol and Chlorpromazine Mediated by Disease-Induced Elevations of Plasma α1Acid GlycoproteinNew England Journal of Medicine, 1978
- Relationship of theophylline clearance to oral dosage in children with chronic asthmaThe Journal of Pediatrics, 1977
- Pharmacokinetics of ethanol after oral administration in the fasting stateJournal of Pharmacokinetics and Biopharmaceutics, 1977
- Pharmacokinetics of carbamazepine in normal humans after single and repeated oral dosesJournal of Pharmacokinetics and Biopharmaceutics, 1976