Urinary excretion of aflatoxin M1 after administration of aflatoxin B1 in sucrose- or starch-rich diets
- 1 September 1978
- journal article
- research article
- Published by Cambridge University Press (CUP) in British Journal of Nutrition
- Vol. 40 (2) , 397-401
- https://doi.org/10.1079/bjn19780137
Abstract
1. Male Sprague–Dawley rats were given 630 g/kg sucrose or starch with 2 mg/kg aflatoxin B1 for periods of 75, 145 and 200 d, and the 24 h urinary excretion of aflatoxin M1 was measured.2. Less aflatoxin M1 was excreted by the rats fed on the sucrose-rich diet compared to those fed on the starch-rich diet. This difference was especially marked when expressed per g metabolizing tissue.3. It is concluded that sucrose probably decreases the activity of aflatoxin B1 metabolism in a similar way to its previously found effect on the drug-metabolizing enzyme.This publication has 9 references indexed in Scilit:
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