The Relation between the Levels of HDL Cholesterol and the Capacity for Removal of Triglycerides

Abstract
In 22 men with normal clinical findings, on exercise ECG and laboratory tests, an i.v. fat tolerance test, and LCAT [lecithin cholesterol acyltransferase] activity and postheparin triglyceride lipase, and serum lipids were estimated. HDL [high density lipoprotein] cholesterol was positively correlated to lipoprotein lipase (r = 0.50, P < 0.05) and to the fractional removal rate of exogenous fat (r = 0.59, P < 0.01), and negatively to the fasting levels of triglycerides (r = -0.65, P < 0.01). LCAT was neither correlated to HDL cholesterol nor to the fat removal rate. A high triglyceride removal capacity is closely correlated to a high level of HDL. The association between the catabolism of triglyceride-rich lipoproteins and HDL was further substantiated. [HDL have been implicated to have a protective role against coronary atherosclerosis.].

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