Overexpression of Functionally Coupled Cyclooxygenase-2 and Prostaglandin E Synthase in Symptomatic Atherosclerotic Plaques as a Basis of Prostaglandin E 2 -Dependent Plaque Instability
- 21 August 2001
- journal article
- other
- Published by Wolters Kluwer Health in Circulation
- Vol. 104 (8) , 921-927
- https://doi.org/10.1161/hc3401.093152
Abstract
Background— Studies have implicated a role for prostaglandin (PG) E2-dependent matrix metalloproteinase (MMP) biosynthesis in the rupture of atherosclerotic plaque. Cyclooxygenase-2 (COX-2) and PGE...Keywords
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