Isolation of sedative principles from Perilla frutescens.
- 1 January 1986
- journal article
- research article
- Published by Pharmaceutical Society of Japan in CHEMICAL & PHARMACEUTICAL BULLETIN
- Vol. 34 (4) , 1672-1677
- https://doi.org/10.1248/cpb.34.1672
Abstract
The MeOH extract of Perilla frutescens leaves, which are used as a sedative in Chinese traditional medicine, was fractionated to isolate its active constituents. The progress of the fractionation was followed by measuring the prolongation of hexobarbital-induced sleep in mice. The activity was mainly due to the presence of both perillaldehyde and stigmasterol.This publication has 3 references indexed in Scilit:
- Pharmacological Studies of Perillae Herba. I. Neuropharmacological Action of Water Extract and PerillaldehydeYAKUGAKU ZASSHI, 1981
- The distribution of dietary plant sterols in serum lipoproteins and liver subcellular fractions of ratsLipids, 1978
- Cholestanol and Plant Sterols in the Adrenal Gland of the Rat.Acta Chemica Scandinavica, 1967