Prevalence of a non-A, non-B-associated antigen/antibody system detected by radioimmunoassay in acute and chronic liver disease
- 1 January 1983
- journal article
- research article
- Published by Wiley in Journal of Medical Virology
- Vol. 12 (4) , 253-265
- https://doi.org/10.1002/jmv.1890120405
Abstract
An antigen/antibody system associated with one form of parenterally transmitted non‐A, non‐B (NANB) hepatitis has been identified by solid‐phase radioimmunoassay (RIA). The antigen is found in 3% of normal subjects and in increased frequency in patients with haemophilia, renal homograft recipients, homosexual men, prostitutes, drug addicts, and patients with chronic hepatitis B virus (HBV) infection. The antigen was found in normal frequency in patients with acute hepatitis A and B, sporadic NANB hepatitis (nondrug addicts), autoimmune and alcohol‐induced chronic liver disease, and primary biliary chirrhosis.Keywords
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