Catalytic tandem addition route to γ,δ-unsaturated carbonyls
- 1 January 1996
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- No. 4,p. 535-536
- https://doi.org/10.1039/cc9960000535
Abstract
Divalent palladium catalysed tandem addition of lithium halides to alkynes and α,β-unsaturated carbonyl compounds gives δ-halo-γ,δ-unsaturated carbonyls in high yield and good stereoselectivity, the key step being the halide assisted protonolysis of the carbon–palladium bond following halopalladation and carbon–carbon double bond insertion.Keywords
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