Effect of Tannic Acid and Related Compounds on the Absorption and Utilization of Proteins in the Rat

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Abstract
Rats fed diets containing various tannins and related phenolics were found to excrete more fecal nitrogen than controls. The excretion of nitrogen was significantly increased with hydrolyzable gallotannin and condensed tannins from quebracho and grape seed. An attempt was made to trace the origin of these fecal nitrogen compounds by the use of 14C-labeled casein, and by proteolytic enzyme assays of intestinal contents and pancreases. Proteins from enzymatic or other endogenous origins rather than the dietary casein appear to constitute a major portion of the excreted nitrogen compounds. Dietary catechin, gallic acid, and ellagic acid have no effect on fecal nitrogen excretion.