Frequency of Candida albicans serotypes in patients with denture-induced stomatitis and in normal denture wearers.

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Abstract
A comparison was made between the serotypes of oral C. albicans taken from patients with denture-induced stomatitis and from a group of age and sex-matched controls. C. albicans isolates were obtained from the fitting surface of the denture, the palatal mucosa supporting the denture and the buccal mucosa. Of the 30 patients in the denture-induced stomatitis group, 29 had only C. albicans serotype A on their palatal mucosa and denture surface; mixtures of serotypes were obtained from the buccal mucosa of these patients. Only 1 patient had serotype B isolates from the palatal mucosa and denture surface. The control group had mixtures of A and B serotypes from both the denture surface and the palatal mucosa, as well as from the buccal sites sampled. Thus, denture-induced stomatitis is evidently associated with the proliferation of a single E. albicans serotype, usually serotype A.

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