gpDB: a database of GPCRs, G-proteins, effectors and their interactions

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Abstract
Summary: gpDB is a publicly accessible, relational database, containing information about G-proteins, G-protein coupled receptors (GPCRs) and effectors, as well as information concerning known interactions between these molecules. The sequences are classified according to a hierarchy of different classes, families and subfamilies based on literature search. The main innovation besides the classification of G-proteins, GPCRs and effectors is the relational model of the database, describing the known coupling specificity of GPCRs to their respective alpha subunits of G-proteins, and also the specific interaction between G-proteins and their effectors, a unique feature not available in any other database. Availability:http://bioinformatics.biol.uoa.gr/gpDB Contact:shamodr@biol.uoa.gr Supplementary information: Supplementary data are available at Bioinformatics online.