19F NMR imaging of cerebral blood flow

Abstract
Techniques for the quantitative imaging assessment of cerebral blood flow are presented in a cat using 19F NMR imaging of trifluoromethane. The input function of the indicator was acquired noninvasively, while its uptake and clearance were followed in 2-cc volume voxels from images acquired at 67 sintervals. A single compartment model yielded normal cerebral blood flow estimates. © 1991 Academic Press, Inc.