Conversion of isopenicillin N into penicillin N in cell-free extracts of Cephalosporium acremonium
- 15 February 1981
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 194 (2) , 645-647
- https://doi.org/10.1042/bj1940645
Abstract
In a cell-free system prepared by osmotic lysis of protoplasts of Cephalosporium acremonium, isopenicillin N is converted into penicillin N. The epimerase activity of the system is labile.This publication has 14 references indexed in Scilit:
- Incorporation of 3H and 14C from (6 α-3H)penicillin N and (10-14C,6 α-3H) penicillin N into deacetoxycephalosporin CBiochemical Journal, 1980
- Cell-free conversion of δ-(l-α-aminoadipyl)-l-cysteinyl-d-valine into an antibiotic with the properties of isopenicillin N in Cephalosporium acremoniumBiochemical Journal, 1979
- Incorporation of 3H from δ-(l-α-amino (4,5-3H)adipyl)-l-cysteinyl-d-(4,4-3H)valine into isopenicillin NBiochemical Journal, 1979
- Synthesis of δ-(α-aminoadipyl)cysteinylvaline and its role in penicillin biosynthesisBiochemical Journal, 1976
- A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye BindingAnalytical Biochemistry, 1976
- Synthesis of tritium-labelled isopenicillin N, penicillin N and 6-aminopenicillanic acidBiochemical Journal, 1975
- Separation, purification and properties of β-lactamase I and β-lactamase II from Bacillus cereus 569/H/9Biochemical Journal, 1974
- Biosynthesis of penicillin N and cephalosporin C. Antibiotic production and other features of the metabolism of a Cephalosporium sp.Biochemical Journal, 1967
- Purification and some properties of cephalosporin N, a new penicillinBiochemical Journal, 1954
- Virulence and Immunogenic Activities ofB. Typhosusin Relation to its Antigenic ConstituentsEpidemiology and Infection, 1935