Separation of pepsinogen II and pepsinogen III from human urine
- 1 May 1964
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 206 (5) , 1106-1110
- https://doi.org/10.1152/ajplegacy.1964.206.5.1106
Abstract
Human urine has been fractionated on diethylaminoethyl cellulose to yield two pepsinogens. They have been called pepsinogen II and pepsinogen III on the basis of chromatographic behavior identical to that of fundic mucosal pepsinogens II and III. Pepsinogen I has been found absent from 23 urine specimens of 12 individuals. Results suggest a gross qualitative and quantitative correlation between pepsinogen II-pepsinogen III ratio (in terms of total proteolytic activity) in urine and gastric mucosa.Keywords
This publication has 3 references indexed in Scilit:
- Separation of pepsin I, pepsin II A, pepsin II B, and pepsin III from human gastric mucosaAmerican Journal of Physiology-Legacy Content, 1963
- The Proteolytic Activity of Gastric JuiceScandinavian Journal of Clinical and Laboratory Investigation, 1955
- UROPEPSIN EXCRETION BY MAN. I. THE SOURCE, PROPERTIES AND ASSAY OF UROPEPSIN 12Journal of Clinical Investigation, 1948