Structural basis for selectivity of a small molecule, S1-binding, submicromolar inhibitor of urokinase-type plasminogen activator
- 1 April 2000
- journal article
- Published by Elsevier in Chemistry & Biology
- Vol. 7 (4) , 299-312
- https://doi.org/10.1016/s1074-5521(00)00104-6
Abstract
No abstract availableKeywords
This publication has 23 references indexed in Scilit:
- On the size of the active site in proteases. I. PapainPublished by Elsevier ,2005
- Emerging therapeutic targets in oncology: urokinase-type plasminogen activator systemEmerging Therapeutic Targets, 1999
- Structural and Functional Analyses of Benzamidine-Based Inhibitors in Complex with Trypsin: Implications for the Inhibition of Factor Xa, tPA, and UrokinaseJournal of Medicinal Chemistry, 1998
- Design of Benzamidine-Type Inhibitors of Factor XaJournal of Medicinal Chemistry, 1998
- Rational Design and Synthesis of Novel, Potent Bis-phenylamidine Carboxylate Factor Xa InhibitorsJournal of Medicinal Chemistry, 1998
- The urokinase-type plasminogen activator system in cancer metastasis: A reviewInternational Journal of Cancer, 1997
- X-ray Structure of Active Site-inhibited Clotting Factor XaPublished by Elsevier ,1996
- The 2.3 Å Crystal Structure of the Catalytic Domain of Recombinant Two-chain Human Tissue-type Plasminogen ActivatorJournal of Molecular Biology, 1996
- The crystal structure of the catalytic domain of human urokinase-type plasminogen activatorStructure, 1995
- Plasminogen Activators, Tissue Degradation, and CancerPublished by Elsevier ,1985