Precocious Puberty

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Abstract
IN the case reported below a small hamartoma attached to the tuber cinereum was associated with precocious puberty without other evidence of Central-nervous-system disease. The correct diagnosis was established after being suggested by pneumoencephalography, refuting an earlier opinion expressed in this journal that only advanced lesions of the hypothalamus, those with additional recognizable symptoms, could be delineated by this method.1 Case ReportA 2–9/12-year-old boy was referred to the University of Washington Hospital because of precocious growth and sexual development. There were no natal or developmental abnormalities. The height and weight were measured in the 50th percentile at 1 year . . .

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