THE PRODUCTION OF SHOCK BY TRAUMA AFTER SPINAL CORD TRANSECTION

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Abstract
Bone and muscle trauma was inflicted upon 4 dogs after recovery from spinal cord transection. Four control expts. without trauma were performed. The adequacy of circulation was detd. by measurements of blood pressure, peripheral blood flow, cardiac output and O2 content of mixed venous blood. The amount of fluid loss into the traumatized area was measured and was kept at a low level by binding the injured extremity. A reduction of blood vol. and hemoconc. occurred after trauma in the presence of a well-maintained circulation and in the absence of excessive blood loss into the injured extremities. Postmortem examinations revealed pathological changes characteristic of shock. These findings suggest the action of some factor capable of causing a reduction in blood vol. not primarily due to excessive local fluid loss or to reduced circulation.

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