A METHOD FOR MEASURING AND THE EFFECT OF ADRENOCORTICOTROPIC HORMONE ON LIPIDSOLUBLE REDUCING SUBSTANCES OF RABBIT PLASMA*

Abstract
A method based on the reduction of phosphomolybdic acid was used for measuring the increase of lipid-soluble reducing substances in the plasma of rabbits after the admn. of ACTH intramusc. Admn. of ACTH to rabbits at 0.4 mg./kg. or greater produced an increase in the plasma reducing value, with a maximum rise in 2 hrs. Lower doses of ACTH were ineffective.