Oral lichen planus: hypersensitivity to dental restoration material

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Abstract
Patients (67) with oral lichen planus of the atrophic-erosive or reticular plaque type were examined. Dental amalgam in contact with mucosal lesions was present in 64 patients and Au fillings in 33. Patch testing with a standard procedure was performed with components of dental fillings. Eleven patients (16%) reacted to at least 1 of the Hg compounds compared to 8% in a reference group. Most positive reactions were caused by elemental Hg and ammoniated Hg. No patient reacted to Au or Cu. Readings at days 10-14 did not increase the number of responders. Thirteen patients were patch tested with Pd, all were negative. It is not clear whether in the Hg positive patients allergy to dental amalgam is a causative or aggravating factor, or merely on epiphenomenon.

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