ELECTROSHOCK‐INDUCED SEIZURES AND THE TURNOVER OF BRAIN PROTEIN IN THE RAT

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Abstract
Abstract— A total of ten electroshock seizures (two seizures per day) were induced in rats beginning 3 days after an injection of [U‐14C]glucose. Despite the intense stimulation, the labelling of the protein and nucleic acid fractions in the brains of convulsed animals decreased only slightly and not significantly. During the first 2 days after administration of [14C]glucose to untreated animals, there was a slight decrease in the specific activity of protein‐bound glutamic acid relative to that of aspartic acid and the total protein fraction, suggesting the presence of a protein with a high content of glutamic acid and a rapid turnover.