A new method for the isolation of ribonucleic acids from mammalian tissues

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Abstract
Ribonucleic acids were prepared from mammalian tissues by extraction with phenol and water at room temperature. Deoxyribonucleic acids remain completely insoluble under the conditions used. Ribonucleic acids were separated from polysaccharides by extraction with 2-methoxyethanol from potassium phosphate solution. Pancreatic ribonuclease was inactivated by the same phenol treatment.