Relationship of Temperature to the Utilization of Glucose for Contractile Force by Cat Heart Muscle

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Abstract
Experiments performed on substrate-depleted cat papillary muscles show that at 37[degree] C there is a 7.6% increase in contractile force after glucose is added, while at 27[degree] C, the increase is 23.7%. When the muscles were maintained at 37[degree]C for 2 hours, and then 27[degree]C for 1 hour, before adding glucose, the increase in force was 28%. All the increases in force are calculated on the basis of the greatest force during the control period. Temperature, as well as spp. must be considered in evaluating the effects of substrates on isolated mammalian heart muscle preparations.

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