Mechanism of the Reaction of Thrombin with Fibrin in a Bovine System
- 1 July 1980
- journal article
- research article
- Published by S. Karger AG in Enzyme
- Vol. 25 (1) , 64-68
- https://doi.org/10.1159/000459218
Abstract
The application of the Freundlich equation suggested by Seegers et al. for the description of thrombin (EC 3.4.21.5) adsorption by fibrin is inadequate in that an exception has to be assumed for the interpretation of the thrombin adsorption by fibrin at higher concentrations of thrombin, and no comprehensive reaction mechanism between thrombin and fibrin is further indicated by this suggestion. Existing data were shown to suggest an interpretation which may provide an explanation for the existing data without irregularity and may have implications for the mechanism of thrombin equilibrium-binding to fibrin.This publication has 4 references indexed in Scilit:
- Equilibrium binding of thrombin to plateletsBiochemistry, 1976
- The binding of kidney-bean phytohemagglutinin by Ehrlich ascites carcinomaBiochimica et Biophysica Acta (BBA) - General Subjects, 1965
- Some physicochemical properties of human fibrinogenBiochemical Journal, 1957
- Multiple Protein Interactions as Exhibited by the Blood-clotting Mechanism.The Journal of Physical Chemistry, 1947