Late Relapse of Clinical Stage I Testicular Cancer

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Abstract
The clinical presentation and treatment of late recurrence (2 or more years after initial management) of testis cancer are defined. A retrospective search was performed to identify patients treated for late relapse at our university from 1979 to 1992 who had initially presented with clinical stage 1 disease. We treated 35 patients with chemotherapy for late relapse. No patient has remained disease-free with chemotherapy alone. Subsequent surgery resulted in 43 percent of the patients being currently disease-free. The treatment of late relapse is surgical. Chemotherapy before late relapse for low volume disease does not uniformly prevent late recurrence.