Increased effect of apomorphine on homovanillic acid in rats terminated from chronic haloperidol
- 1 June 1978
- journal article
- research article
- Published by Springer Nature in Journal Of Neural Transmission-Parkinsons Disease and Dementia Section
- Vol. 42 (2) , 159-162
- https://doi.org/10.1007/bf01675355
Abstract
Rats who where administered apomorphine seven days after termination of chronic treatment with haloperidol had significantly (59%) lower level of brain HVA than saline control rats. This finding is consistent with the behavioral evidence suggesting supersensitivity of post-synaptic dopamine receptors after termination of chronic haloperidol.This publication has 16 references indexed in Scilit:
- Antischizophrenic Drugs: Chronic Treatment Elevates Dopamine Receptor Binding in BrainScience, 1977
- Behavioral evidence for supersensitivity after chronic administration of haloperidol, clozapine, and thioridazineLife Sciences, 1976
- Behavioural supersensitivity to apomorphine following chronic treatment with drugs which interfere with the synaptic function of catecholaminesNeuropharmacology, 1974
- Behavioral evidence for dopaminergic supersensitivity after chronic haloperidolLife Sciences, 1974
- The use of isomeric compounds as internal standards for quantitative mass fragmentography of biological samples. Determination of homovanillic acid in cerebrospinal fluid and plasmaBiochemical and Biophysical Research Communications, 1974
- Rapid elevation of biogenic amine metabolites in human CSF following probenecidLife Sciences, 1970
- Decrease in homovanillic acid as evidence for dopamine receptor stimulation by apomorphine in the neostriatum of the ratJournal of Pharmacy and Pharmacology, 1969
- Evidence for dopamine receptor stimulation by apomorphineJournal of Pharmacy and Pharmacology, 1967
- Effect of Probenecid on the Levels of Monoamine Metabolites in the Rat BrainActa Pharmacologica et Toxicologica, 1967
- REGIONAL STUDIES OF CATECHOLAMINES IN THE RAT BRAIN‐IJournal of Neurochemistry, 1966