Ly316340: A potent HIV-1 protease inhibitor containing a high affinity octahydrothienopyridine hydroxyethylamine isostere
- 7 December 1995
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 5 (23) , 2885-2890
- https://doi.org/10.1016/0960-894x(95)00506-o
Abstract
No abstract availableKeywords
This publication has 16 references indexed in Scilit:
- Structure-based drug design of nonpeptidic P2 substituents for HIV-1 protease inhibitorsBioorganic & Medicinal Chemistry Letters, 1995
- Cyclic sulfone-3-carboxamides as novel P2-ligands for Ro 31-8959 based HIV-1 protease inhibitorsBioorganic & Medicinal Chemistry Letters, 1995
- The Development of Cyclic Sulfolanes as Novel and High-Affinity P2 Ligands for HIV-1 Protease InhibitorsJournal of Medicinal Chemistry, 1994
- Chapter 14. HIV Protease InhibitorsPublished by Elsevier ,1994
- Cyclic sulfolanes as novel and high-affinity P2 ligands for HIV-1 protease inhibitorsJournal of Medicinal Chemistry, 1993
- 3-Tetrahydrofuran and pyran urethanes as high-affinity P2-ligands for HIV-1 protease inhibitorsJournal of Medicinal Chemistry, 1993
- 3'-Tetrahydrofuranylglycine as a novel, unnatural amino acid surrogate for asparagine in the design of inhibitors of the HIV proteaseJournal of the American Chemical Society, 1993
- Ro-31-8959/003Drugs of the Future, 1991
- Rational Design of Peptide-Based HIV Proteinase InhibitorsScience, 1990
- Structure of Complex of Synthetic HIV-1 Protease with a Substrate-Based Inhibitor at 2.3 Å ResolutionScience, 1989