HLA‐A, B Haplotype Frequencies in 5,202 Unrelated Danes by a Maximum‐Likelihood Method of Gene Counting

Abstract
A population sample of 5,202 persons comprising normal, healthy individuals from three laboratories in Copenhagen was used for estimating HLA‐A, ‐B antigen, gene, and haplotype frequencies, besides delta‐values and their standard errors. The serum panels used allowed the determination of a total of 273 HLA‐A, ‐B haplotypes, and the most significant Δ‐values were in agreement with those found in other Caucasian populations. The methods used for the calculations of frequencies, delta‐values, and standard errors are described.