Localization of papillomavirus and virus-specific antigens in the skin of tumor-bearingMastomys natalensis (GRA Giessen)
- 1 July 1978
- journal article
- research article
- Published by Springer Nature in Medical Microbiology and Immunology
- Vol. 165 (2) , 93-99
- https://doi.org/10.1007/bf02122744
Abstract
In skin neoplasms (so-called keratoakanthomas, papillomas, and squamous cell carcinomas) ofMastomys natalensis (GRA Giessen) virus particles and viral antigens were demonstrated in distinct epithelial layers. Nuclei of the upper parts of the stratum granulosum and disintegrated cell parts of the stratum corneum contain viral structures. The localization of virus particles and viral antigens in any skin neoplasms ofM. natalensis (GRA Giessen) corresponded to the sites where papillomavirus-specific material had been demonstrated in papillomas of other species.Keywords
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