Effect of Bilateral Adrenalectomy on the Cardiovascular Response to Induced Tachycardia.

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Abstract
Summary Relatively short bouts of electrically induced ventricular tachycardia of sufficiently high rate to result at least initially in a marked decrease in cardiac output and mean arterial blood pressure were induced in anesthetized dogs before and immediately after bilateral adrenalectomy. This study reveals that, although adrenalectomy affects the circulation under the experimental circumstances described, the degree of cardiovascular compensation in response to such bouts of tachycardia can remain relatively unaffected by bilateral adrenalectomy. Whether this remains true with bouts of higher rate tachycardia remains to be determined.