Concentration-Controlled or Effect-Controlled Trials
- 1 January 2001
- journal article
- review article
- Published by Springer Nature in Clinical Pharmacokinetics
- Vol. 40 (5) , 317-325
- https://doi.org/10.2165/00003088-200140050-00001
Abstract
Historically, dose-finding trials have been confirmatory in nature despite the fact that these trials represent an important and essential ‘learning’ phase in the drug development process. About 10...Keywords
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