Phorbol Myristate Acetate Enhances Adenylate Cyclase Activity in Human Polymorphonuclear Leukocytes
- 14 March 1990
- journal article
- research article
- Published by Georg Thieme Verlag KG in Hormone and Metabolic Research
- Vol. 22 (03) , 175-178
- https://doi.org/10.1055/s-2007-1004877
Abstract
The putative role of protein phosphorylation in modulating adenylate cyclase activity in polymorphonuclear neutrophil membranes was assessed using phorbol myristate acetate (PMA) to stimulate the activity of protein kinase C. PMA was demonstrated to enhance the adenylate cyclase activity stimulated by isoproterenol.Keywords
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