Modification of the system of screening for antisyphilis antibodies in a blood transfusion centre, featuring a miniaturisation of the Treponema pallidum haemagglutination assay.

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Abstract
A modified, miniatured version of the Fujizoki T. pallidum hemagglutination assay (TPHA) is described. The method is fast, sensitive, specific and very economical. During a test period of 1 yr, use of the method gave rise to a 67% increase in confirmed positive among new donor sera and a 112.5% increase among the antenatal sera over the numbers that would have been detected using a cardiolipin test alone. With the new donor sera, the rate of confirmed positives detected during the test period was 150% greater than that of 1980, when a cardiolipin test alone was used (0.05 > P > 0.02 (.chi.2 test)).