Dependence of cytoplasmic on mitochondrial protein synthesis inK. lactis CBS 2360
- 1 January 1977
- journal article
- research article
- Published by Springer Nature in Molecular Genetics and Genomics
- Vol. 150 (2) , 141-145
- https://doi.org/10.1007/bf00695394
Abstract
A fewery R mutants independently isolated fromK. lactis CBS 2360 display a conditional lethal phenotype at the temperature of 36° C. In addition to drug resistance, also conditional lethality shows a non-Mendelian pattern of inheritance and is affected by exposure of the cells to Ethidium Bromide, indicating that in this yeast mitochondrial DNA controls cell viability. The results obtained from biochemical analysis suggest that the cellular functions in which are involved the gene products of the mitochondrial mutants analized are cytoplasmic protein and RNA syntheses.This publication has 10 references indexed in Scilit:
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