Antithrombin III: Protection against Death after Injection of Thromboplastin
- 24 October 1969
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 166 (3904) , 517-518
- https://doi.org/10.1126/science.166.3904.517
Abstract
Intravenous injection of autologous lipoprotein (thromboplastin) or thrombin produced a lethal, hemorrhagic syndrome in chicken embryos. The embryos could be protected from this fatal result by injection of antithrombin III, an alpha2-globulin (molecular weight 60,000 to 80,000) purified from human, bovine, and guinea pig blood. Heparin also protected the embryos, but other inhibitors were less protective.Keywords
This publication has 5 references indexed in Scilit:
- Symposium on 5-HydroxytryptamineScandinavian Journal of Clinical and Laboratory Investigation, 1968
- Purification of Two Progressive Antithrombins of Human PlasmaScandinavian Journal of Clinical and Laboratory Investigation, 1967
- Dissociation of Esterolytic and Clotting Activities of Thrombin by Trypsin-Binding Macroglobulin.Experimental Biology and Medicine, 1966
- Some experimental factors in the gradient chromatography of serum proteinsArchives of Biochemistry and Biophysics, 1962
- THE ACTIVE PRINCIPLE OF PLACENTAL TOXIN: THROMBOPLASTIN; ITS INACTIVATOR IN BLOOD: ANTITHROMBOPLASTINAmerican Journal of Physiology-Legacy Content, 1947