Sesquiterpenoid stress compounds of Datura stramonium: biosynthesis of the three major metabolites from [1,2-13C]acetate and the X-ray structure of 3-hydroxylubimin

Abstract
2,3-Germacrenediol, lubimin, and hydroxylubimin, the major stress metabolites of Datura stramonium, incorporate sodium [1,2-13C]acetate in patterns, as shown by 13C n.m.r. spectroscopy, which establish their structures and mevalonate origins; the X-ray structure of hydroxylubimin completely defines its stereochemistry.

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