STUDIES ON GRANULATION TISSUE PRODUCTION IN ALLOXAN-DIABETIC RATS
- 1 April 1961
- journal article
- research article
- Published by Bioscientifica in Journal of Endocrinology
- Vol. 22 (2) , 143-146
- https://doi.org/10.1677/joe.0.0220143
Abstract
SUMMARY: Alloxan-diabetic rats produce significantly less granulation tissue than normal ones. Locally applied growth hormone (STH), which stimulates granulation tissue in normal rats, lost this ability in diabetic animals. Adrenalectomized alloxan-diabetic rats also fail to respond by increased granulation tissue growth to STH. The stimulation of granulation tissue by STH seems to depend on an adequate supply of insulin.Keywords
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