COMBINED EFFECT OF SPACE-FLIGHT AND RADIATION ON SKELETAL-MUSCLES OF RATS

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  • 1 January 1977
    • journal article
    • research article
    • Vol. 48  (2) , 115-119
Abstract
Skeletal muscles of rats flown for 20.5 days aboard the biosatellite Cosmos-690 and irradiated with a dose of 800 rad on the 10th flight day were studied. The radiation exposure aggravated the severity of atrophic and dystrophic processes in m. [musculus] soleus and atrophic process in m. gastrocnemius that developed under the conditions of weightlessness and hypokinesia. At the same time an exposure to penetrating radiation did not affect the muscles where no flight-induced pathologies occurred. The radiation affected the pattern of reparation in those regions of the soleus muscle that developed pathology inflight, slowed down resorption of the connective tissue formed during the pathological process and inhibited the course of the reparative process.